Apoptosis Reagents and Kits
Abcam Lysosomal Staining Reagent - Green - Cytopainter.
Lysosomal Staining Reagent - Green - Cytopainter.
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Annexin V-Cy5/DAPI Apoptosis Kit 50assays
Annexin V is a Ca2 -dependent phospholipid-binding protein that specifically binds to phosphatidylserine (PS) Normally PS is localized on the inner leaflet of the cell membrane lipid bilayer During the early stages of apoptosis PS translocates from the inner leaflet to the outer surface of the cell membrane exposing it to the extracellular environment Due to Annexin V s high affinity for PS fluorescently labeled Annexin V (Cy5) can be used as a fluorescent probe to detect apoptotic cells through flow cytometry or fluorescence microscopy with staining taking only 10-20 minutes DAPI specifically binds to double-stranded DNA emitting blue fluorescence but normally cannot permeate intact cell membranes However DAPI can enter late-stage apoptotic or dead cells and stain their nuclei Simultaneous staining with Annexin V-Cy5 and DAPI allows differentiation of cells at various stages of apoptosis and cell death
Medchemexpress LLC N-(Benzyloxycarbonyl)-D-homoserine | 41088-85-1 | MFCD12545887 | 253.25 | C12H15NO5 | 1 G
N-(Benzyloxycarbonyl)-D-homoserine is the D-enantiomer of homoserine bearing an N-carbobenzoxy (Cbz) protecting group. Supplied as a powder, it is used as a drug intermediate in small-molecule synthesis and can be employed in the preparation of antibody-drug conjugates (ADCs). Molecular formula C12H15NO5; molecular weight 253.25. Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Protected amino group enables selective synthetic transformations.
- Suitable for use as a drug intermediate in medicinal chemistry workflows.
- Powder form supports convenient handling and long-term storage.
- Defined molecular formula and mass aid analytical characterization.
- Established storage recommendations help preserve compound stability.
Abcam Human TK1 (Thymidine Kinase 1) knockout HEK-293T cell lysate.
Human TK1 (Thymidine Kinase 1) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
CPC Scientific Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Tyr-Val-Ala-Asp-CHO 0.5MG
Cell permeable inhibitor of caspase-1.ONE-LETTER SEQUENCE: Ac-AAVALLPAVLLALLAPYVAD-CHOMOLECULAR FORMULA: C97H160N20O24MOLECULAR WEIGHT:1990.46STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [201608-12-0], SYNONYMS: Cell-permeable Caspase-1 Inhibitor IRESEARCH AREA: ApoptosisREFERENCES: Y.-Z. Lin et al., J. Biol. Chem., 271, 5305 (1996); L.A. Reiter, Int. J. Pept. Protein Res., 43, 87 (1994); N.A. Thornberry et al., Biochemistry, 33, 3934 (1994)
Eurofins Discoverx KILR SKOV3 (Human) Cytotoxicity Assay Kit (cell pool)
The KILR SKOV3 (Human) Stable Cell Pool Cytotoxicity Assay utilizes the engineered stable target cell pool that is used to measure direct death mediated by immuno-oncology treatments via ADCC, CDC, and ADCP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx KILR U2OS (Human) PD-L2 Cytotoxicity Assay Kit (Clone)
The KILR U2OS Human PD-L2 Stable Cell Line Cytotoxicity Assay (U2OS) utilizes the stable, engineered U2OS-PD-L2 target cell line for quantifying effector-induced cell death. This assay enables measurement of immune cell-mediated killing through ADCC, ADCP and CDC. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Abcam MMP2 Inhibitor Screening Assay Kit (Fluorometric).
MMP2 Inhibitor Screening Assay Kit (Fluorometric).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human TPM4 knockout HEK-293T cell lysate.
Human TPM4 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human FYN knockout HEK-293 cell lysate.
Human FYN knockout HEK-293 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Meso Scale Discovery R-PLEX Human Caspase-1 ASYQP
The R-Plex Human Caspase-1 Assay Kit from Meso Scale Discovery is used to quantitatively measure caspase-1 in human biological samples such as serum plasma cell culture supernatants and cell lysates The assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity a broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an ECL tag and calibrator diluent The assay takes approximately 3 5 hours to complete after a 2 hour incubation period The kit can perform up to 94 assays in the 96-well plate format
Abcam Human B2M (beta 2 Microglobulin) knockout Hep G2 cell lysate.
Human B2M (beta 2 Microglobulin) knockout Hep G2 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Enzo Life Sciences Apoptosis Activator 2 (25mg). CAS: 79183-19-0
Induces apoptosis by promoting the oligomerization of Apaf-1 into the mature, functional apoptosome, triggering caspase-9 activation resulting in activated caspase-3. Shows strong selectivity for cancer cells against normal cell lines. Acts in a similar way like apoptosis inducer PETCM (ALX-420-031). Alternative name: 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (5mg/ml), methanol (5mg/ml) or 100% ethanol. Long Term Storage: +4°C.
Medchemexpress LLC N-carbobenzoxy-D-homoserine (N-(benzyloxycarbonyl)-D-homoserine) | 41088-85-1 | MFCD12545887 | >98.0% | 253.25 g·mol⁻¹ | C12H15NO5 | 10 G
N-Carbobenzoxy-D-homoserine (N-(Benzyloxycarbonyl)-D-homoserine) is a Cbz-protected D-homoserine used as a synthetic intermediate and building block in medicinal chemistry. It is employed in the preparation of antibody-drug conjugates and peptides, providing a protected amino acid handle for selective coupling and downstream functionalization.
- Cbz-protected amino acid for selective N-protection.
- Suitable intermediate for antibody-drug conjugate synthesis.
- Compatible with peptide and amide bond formation chemistries.
- Stable as a powder with defined low-temperature storage recommendations.
- Characterized by a known molecular formula and molecular weight for analytical use.
Cayman Chemical Stm Cel Smal Molcule Scre 50uL
An Asc-1 inhibitor selectively inhibits Asc-1 in HEK293 cells expressing Asc-1 (IC50 36.8 nM) over 40 other transporters (IC50s >10 UM) inhibits serine cysteine glycine and alanine import and cAMP-induced increases in the OCR and decreases UCP1 levels in primary human white and brown adipose cells at 100 nM decreases the number of malformed neurons and reduces contextual fear memory deficits in a mouse model of surgery-induced brain damage when intracerebroventricularly infused